INSULIN LIPOHYPERTROPHY: A NON-FATAL DERMATOLOGICAL COMPLICATION OF DIABETES MELLITUS REFLECTING POOR GLYCEMIC CONTROL

Insulin lipohypertrophy: A non-fatal dermatological complication of diabetes mellitus reflecting poor glycemic control

Lipohypertrophy has been a recognized complication of insulin therapy.Despite improvements in insulin purity and the introduction of recombinant human insulin, its prevalence has remained high particularly in those with a poor glycemic control.Injection of insulin into a site of lipohypertrophy, although painless, may lead to erratic absorption of

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The impact of anionic polymers on gene delivery: how composition and assembly help evading the toxicity-efficiency dilemma

Abstract Cationic polymers have been widely studied for non-viral gene delivery due to their ability to bind genetic material and to interact with cellular membranes.However, their charged nature carries the risk of increased cytotoxicity and interaction pata de avestruz botas with serum proteins, limiting their potential in vivo application.Theref

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Optimization of hoisting parameters in a multi-rope friction mine hoist based on the multi-source coupled vibration characteristics of hoisting catenaries

To avoid catenary collision in a multi-rope friction mine hoist, in this study, the relevant hoisting parameters based on the multi-source coupled vibration characteristics of hoisting catenaries are optimized.First, the multi-source coupled vibration characteristics of hoisting catenaries were investigated based on an established theoretical model

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